(2-(2-Cyanophenyl)pyrimidin-5-yl)boronic acid CAS 2225177-99-9
| CAS No. | 2225177-99-9 |
| Molecular Formula | C11H8BN3O2 |
| Molecular Weight | 225.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-(2-Cyanophenyl)pyrimidin-5-yl)boronic acid.
CATO supplies (2-(2-Cyanophenyl)pyrimidin-5-yl)boronic acid (CAS 2225177-99-9), a certified reference material (molecular formula C11H8BN3O2, MW 225.01 g/mol) for analytical method development and quality control.
The molecular framework of (2-(2-Cyanophenyl)pyrimidin-5-yl)boronic acid (C11H8BN3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2-(2-Cyanophenyl)pyrimidin-5-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8BN3O2 |
| Molecular Weight | 225.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
Related Cyanophenyl Standards
- (2-(3-Cyanophenyl)pyrimidin-5-yl)boronic acid (CAS 2225177-24-0)
- (2-(4-Cyanophenyl)pyrimidin-5-yl)boronic acid (CAS 2095608-22-1)
- Ethyl 2-(3-Cyanophenyl)-2,2-difluoroacetate (CAS 1249788-93-9)
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- Ethyl 2-(4-Cyanophenyl)-2,2-difluoroacetate (CAS 854778-10-2)
- 1-(4-Cyanophenyl)-N,N-dimethylmethanesulfonamide (CAS 1036479-03-4)
- 1-(2-Cyanophenyl)-N,N-dimethylmethanesulfonamide (CAS 1036501-57-1)
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Recommended Standards
- 1-Bromo-2,3-difluoro-5-(fluoromethyl)benzene (CAS 1785082-71-4)
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- 1-Bromo-2,5-difluoro-4-(fluoromethyl)benzene (CAS 2244083-92-7)
- 1-(3-Piperidinyl)-3-pyrrolidinol dihydrochloride (CAS 1219957-20-6)
- Methyl 2-(4-(tert-butoxy)phenyl)acetate (CAS 87100-56-9)
- Sambacolignoside (CAS 114449-12-6)
- 3-(4-methoxyphenyl)-6-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1018143-33-3)
- 4-(3-(Dimethylamino)pyrrolidin-1-yl)pyridin-3-amine (CAS 1342621-71-9)
- 2-(5-Amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one (CAS 1207047-57-1)
- 1-(3-(((2-Hydroxyethyl)(isopropyl)amino)methyl)piperidin-1-yl)ethanone (CAS 1353963-94-6)
- 2-Fluoro-N,N-dimethyl-5-sulfamoylbenzamide (CAS 1496857-22-7)
- 3-(3-aminophenyl)-5-cyclopropyl-5-methylimidazolidine-2,4-dione (CAS 1485279-07-9)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
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