(2-Chloro-3-cyclopropylphenyl)boronic acid CAS 2225178-18-5
| CAS No. | 2225178-18-5 |
| Molecular Formula | C9H10BClO2 |
| Molecular Weight | 196.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (2-Chloro-3-cyclopropylphenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(2-Chloro-3-cyclopropylphenyl)boronic acid (CAS 2225178-18-5), molecular formula C9H10BClO2 and molecular weight 196.44 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-Chloro-3-cyclopropylphenyl)boronic acid (C9H10BClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H10BClO2 |
| Molecular Weight | 196.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- (4-Chloro-3-cyclopropylphenyl)boronic acid (CAS 1548739-71-4)
- (4-Chloro-2-cyclopropylphenyl)boronic acid (CAS 1824647-96-2)
- (2-Chloro-4-cyclopropylphenyl)boronic acid (CAS 2225175-17-5)
- (2-Chloro-5-cyclopropylphenyl)boronic acid (CAS 2225180-84-5)
- (2-Chloro-6-cyclopropylphenyl)boronic acid (CAS 2225175-57-3)
- (3-Chloro-2-cyclopropylphenyl)boronic acid (CAS 2225178-23-2)
- (3-Chloro-4-cyclopropylphenyl)boronic acid (CAS 2225155-20-2)
- (3-Chloro-5-cyclopropylphenyl)boronic acid (CAS 2225170-80-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com