(3-Chloro-5-methoxy-2-methylphenyl)boronic acid CAS 2225178-57-2
| CAS No. | 2225178-57-2 |
| Molecular Formula | C8H10BClO3 |
| Molecular Weight | 200.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (3-Chloro-5-methoxy-2-methylphenyl)boronic acid (CAS 2225178-57-2), a certified reference material (molecular formula C8H10BClO3, MW 200.43 g/mol) for analytical method development and quality control.
The molecular framework of (3-Chloro-5-methoxy-2-methylphenyl)boronic acid (C8H10BClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (3-Chloro-5-methoxy-2-methylphenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10BClO3 |
| Molecular Weight | 200.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 3-Chloro-4-methoxy-5-methylphenylboronic acid (CAS 1050509-76-6)
- (4-Chloro-2-(methoxymethyl)phenyl)boronic acid (CAS 1208318-89-1)
- 2-Chloro-3-ethoxyphenylboronic acid (CAS 1256345-57-9)
- (3-Chloro-5-ethoxyphenyl)boronic acid (CAS 1256345-73-9)
- (4-Chloro-3-(methoxymethyl)phenyl)boronic acid (CAS 1392415-54-1)
- 2-Chloro-5-methoxymethylphenylboronic acid (CAS 1451392-23-6)
- 5-Chloro-6-(dimethylamino)pyridin-3-ylboronic acid (CAS 1704121-36-7)
- (2-Chloro-4-isopropylpyrimidin-5-yl)boronic acid (CAS 2225180-56-1)
Recommended Standards
- (3-Chloro-4-ethoxyphenyl)boronic acid (CAS 279261-81-3)
- (4-Chloro-2-isopropylpyrimidin-5-yl)boronic acid (CAS 2225174-09-2)
- (3-Chloro-2-methoxy-4-methylphenyl)boronic acid (CAS 2121511-90-6)
- (4-Chloro-2-propylpyrimidin-5-yl)boronic acid (CAS 2225177-29-5)
- 2-(5-Aminopentyl)-3H-imidazo[4,5-b]pyridin-5-amine (CAS 1542337-26-7)
- 4-(Difluoromethyl)thiophen-3-amine (CAS 2002442-01-3)
- 2-[Butyl[(Pentadecafluoroheptyl)Sulphonyl]Amino]Ethyl Acrylate (CAS 68298-60-2)
- N1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]propane-1,3-diamine (CAS 465514-63-0)
- Potassium Trifluoro(3-hydroxyphenyl)borate (CAS 871231-45-7)
- 4-CHloro-1,1-difluorobut-1-ene (CAS 1346521-43-4)
- 3-(Cyclohexyloxy)-4-hydroxybenzenesulfonamide (CAS 1243461-40-6)
- 5-Bromo-3-((trifluoromethyl)thio)pyridin-2-amine (CAS 1637399-40-6)
- Amino(dimethoxyphosphoryl)methyl acetate oxalate (CAS 89537-22-4)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
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