(2-(Tert-butyl)-6-(trifluoromethyl)pyridin-4-yl)boronic acid CAS 2225179-66-6
| CAS No. | 2225179-66-6 |
| Molecular Formula | C10H13BF3NO2 |
| Molecular Weight | 247.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2-(Tert-butyl)-6-(trifluoromethyl)pyridin-4-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2-(Tert-butyl)-6-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2225179-66-6), molecular formula C10H13BF3NO2 and molecular weight 247.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-(Tert-butyl)-6-(trifluoromethyl)pyridin-4-yl)boronic acid (C10H13BF3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H13BF3NO2 |
| Molecular Weight | 247.02 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2-(Tert-butyl)-5-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225179-92-8)
- (5-(Sec-butyl)-6-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225153-39-7)
- (4-((2-Nitro-1H-imidazol-1-yl)methyl)phenyl)boronic acid (CAS 137756-87-7)
- (5-(Tert-butyl)-2-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2225170-96-5)
- Ethyl 2-bromo-3-chloro-6-fluorobenzoate (CAS 1805478-71-0)
- Butyl thiomorpholine-3-carboxylate (CAS 1543541-74-7)
- 3-(4-(Trifluoromethoxy)phenyl)acrylaldehyde (CAS 681484-59-3)
- 1,2-Dibromo-1-((trifluoromethyl)sulfonyl)ethane (CAS 26186-60-7)
- 7-Azaindole-6-carboxylic Acid (CAS 898746-35-5)
- 2-Methoxy-4-(trifluoromethyl)pyrimidine-5-carboxylic acid (CAS 1202980-50-4)
- (3S,4S)-tert-Butyl 3-amino-4-methoxypiperidine-1-carboxylate (CAS 1207853-84-6)
- N,N-dimethyl-2-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)ethan-1-amine (CAS 892501-92-7)
- 2-(cyclopropylmethyl)-1,3-oxazole-4-carboxylic acid (CAS 1249719-58-1)
- Macrocyclic Peptide flaviviridae Viruses InhibitorDISCONTINUED (CAS 1510841-23-2)
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