(5-Bromo-6-(1H-pyrazol-1-yl)pyridin-3-yl)boronic acid CAS 2225180-80-1

Purity 97%+In StockPharmaceutical Standards
CAS No.2225180-80-1
Molecular FormulaC8H7BBrN3O2
Molecular Weight267.88 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-Bromo-6-(1H-pyrazol-1-yl)pyridin-3-yl)boronic acid CAS 2225180-80-1 chemical structure

Description

The occurrence of (5-Bromo-6-(1H-pyrazol-1-yl)pyridin-3-yl)boronic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (5-Bromo-6-(1H-pyrazol-1-yl)pyridin-3-yl)boronic acid (CAS 2225180-80-1), a certified reference material (molecular formula C8H7BBrN3O2, MW 267.88 g/mol) for analytical method development and quality control.

(5-Bromo-6-(1H-pyrazol-1-yl)pyridin-3-yl)boronic acid (C8H7BBrN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (5-Bromo-6-(1H-pyrazol-1-yl)pyridin-3-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H7BBrN3O2
Molecular Weight267.88 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentBr-containing
Nitrogen Atoms3

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