Ethyl (R)-3-amino-3-(3-fluoro-4-methoxyphenyl)propanoate hydrochloride CAS 2226159-96-0
| CAS No. | 2226159-96-0 |
| Molecular Formula | C12H16FNO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Ethyl (R)-3-amino-3-(3-fluoro-4-methoxyphenyl)propanoate hydrochloride (CAS 2226159-96-0), a certified reference material (molecular formula C12H16FNO3HCl, MW 277.72 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl (R)-3-amino-3-(3-fluoro-4-methoxyphenyl)propanoate hydrochloride (C12H16FNO3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Ethyl (R)-3-amino-3-(3-fluoro-4-methoxyphenyl)propanoate hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16FNO3 HCl |
| Molecular Weight | 277.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3S,4S)-3-(Boc-amino)-4-methylpyrrolidine (CAS 127199-54-6)
- n-Octyl-Xanthate, Potassium Salt (CAS 2720-80-1)
- 2-((2-Chloroethyl)amino)-1,4-dihydroxyanthracene-9,10-dione (CAS 62418-36-4)
- 1-(Benzo[d][1,3]dioxol-5-yl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1533157-19-5)
- Methyl 4-bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole-3-carboxylate (CAS 1654727-04-4)
- N-phenyl-3,4-dihydroquinoline-1(2H)-carboxamide (CAS 349454-54-2)
- (R)-2-(3-Methoxypiperidin-1-yl)ethanamine (CAS 1354011-96-3)
- Dioctadecylbis(3-phenylpropyl)silane (CAS 18822-34-9)
- 2-(Chloromethyl)-4-cyano-3-(difluoromethyl)pyridine-6-acetic acid (CAS 1805430-54-9)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com