Esomeprazol Impurity H431 (Ammonium Salt) CAS 2227107-89-1
| CAS No. | 2227107-89-1 |
| Molecular Formula | C16H14N3O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Esomeprazol Impurity H431 (Ammonium Salt) (CAS 2227107-89-1), a pharmacopoeial impurity reference standard (molecular formula C16H14N3O4H4N, MW 330.34 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Esomeprazol Impurity H431 (Ammonium Salt) (C16H14N3O4H4N) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Esomeprazol Impurity H431 (Ammonium Salt) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14N3O4 H4N |
| Molecular Weight | 330.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 4 |
Related Esomeprazol Standards
Recommended Standards
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- Olanzapine Embonate Monohydrate EP Impurity F (CAS CATO-C4X-117863)
- Urapidil Impurity 108 (CAS CATO-C4X-1924108)
- Heterophyllin B (CAS 145459-19-4)
- tert-butyl (2S,4S)-4-azido-2-(methoxymethyl)pyrrolidine-1-carboxylate (CAS 348165-53-7)
- 5-(hydroxymethyl)-5-(propan-2-yl)piperidin-2-one (CAS 1909337-78-5)
- (6,7-Dimethoxyisoquinolin-1-yl)(3,4-dimethoxyphenyl)methanamine (CAS 39964-73-3)
- 2,3-Dihydro-1H-isoindole-2-sulfonyl chloride (CAS 145691-51-6)
- Ethyl 5-((ethylsulfonyl)methyl)-4,5-dihydroisoxazole-3-carboxylate (CAS 1707403-05-1)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
Why CATO?
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