2-Bromo-6-chloro-4-fluoroanisole CAS 222712-93-8
| CAS No. | 222712-93-8 |
| Molecular Formula | C7H5BrClFO |
| Molecular Weight | 239.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Bromo-6-chloro-4-fluoroanisole (CAS 222712-93-8), a certified reference material (molecular formula C7H5BrClFO, MW 239.47 g/mol) for analytical method development and quality control.
Structurally, 2-Bromo-6-chloro-4-fluoroanisole (C7H5BrClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 239.47 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Bromo-6-chloro-4-fluoroanisole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrClFO |
| Molecular Weight | 239.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- (2-Bromo-4-chloro-5-fluorophenyl)methanol (CAS 1067882-62-5)
- 2-Bromo-4-chloro-1-fluoro-3-methoxybenzene (CAS 1208074-84-3)
- 5-Bromo-2-chloro-1-fluoro-3-methoxybenzene (CAS 1261216-28-7)
- 4-Bromo-2-chloro-5-fluorobenzyl alcohol (CAS 1338254-21-9)
- 1-Bromo-4-chloro-3-fluoro-2-methoxybenzene (CAS 1414870-75-9)
- (2-Bromo-4-chloro-6-fluorophenyl)methanol (CAS 1449008-26-7)
- (6-Bromo-3-chloro-2-fluorophenyl)methanol (CAS 1449008-28-9)
- 1-Bromo-4-chloro-2-fluoro-5-methoxybenzene (CAS 146447-18-9)
Recommended Standards
- 2-Bromo-4-chloro-6-fluoroanisole (CAS 886499-78-1)
- 5-bromo-1-chloro-3-fluoro-2-methoxybenzene (CAS 261762-34-9)
- 2-Bromo-1-chloro-5-fluoro-3-methoxybenzene (CAS 2090550-06-2)
- 5-Bromo-3-chloro-4-fluorobenzene-1,2-diamine (CAS 2728217-75-0)
- 3-(Dibutylamino)propyl acrylate (CAS 6288-21-7)
- Ethyl (E)-5-methylhex-2-enoate (CAS 2351-89-5)
- N-(4-((2-Hydroxyethyl)amino)cyclohexyl)-N-methylacetamide (CAS 1353988-30-3)
- Pyrazin-2-yl(3-(trifluoromethyl)phenyl)methanone (CAS 174813-01-5)
- 2-(Tribromomethyl)quinoxaline (CAS 7251-36-7)
- 1-(4-Methyl-2-(2,4,5-trichlorophenoxy)pyrimidin-5-yl)ethan-1-one (CAS 478047-63-1)
- 3-Nitrooxetane (CAS 86632-92-0)
- 2',6'-Difluoro-[1,1'-biphenyl]-3-amine (CAS 851462-21-0)
- (2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4,4-difluoro-Butanoic acid (CAS 467442-21-3)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
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