(4R)-4-(fluoromethyl)-1,3-oxazolidin-2-one CAS 2227197-78-4
| CAS No. | 2227197-78-4 |
| Molecular Formula | C4H6FNO2 |
| Molecular Weight | 119.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (4R)-4-(fluoromethyl)-1,3-oxazolidin-2-one (CAS 2227197-78-4), a certified reference material (molecular formula C4H6FNO2, MW 119.09 g/mol) for analytical method development and quality control.
The molecular framework of (4R)-4-(fluoromethyl)-1,3-oxazolidin-2-one (C4H6FNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6FNO2 |
| Molecular Weight | 119.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- (S)-4-(fluoromethyl)oxazolidin-2-one (CAS 2059155-17-6)
- 4-(Fluoromethyl)oxazolidin-2-one (CAS 2229098-22-8)
- (S)-3-(Fluoromethyl)morpholine (CAS 1266323-76-5)
- 3-(Fluoromethyl)pyrrolidin-3-ol (CAS 1419209-33-8)
- [3-(Fluoromethyl)oxetan-3-yl]methanamine (CAS 1781044-26-5)
- (3-(Fluoromethyl)azetidin-3-yl)methanol (CAS 2231674-26-1)
- (R)-3-(Fluoromethyl)morpholine (CAS 793652-02-5)
- 2-(Fluoromethyl)morpholine (CAS 737730-98-2)
Recommended Standards
- (2R,3R)-3-Fluoroazetidine-2-carboxylic acid (CAS 1932581-59-3)
- 4-oxopentanoic-3,4,5-13C3 acid (CAS 1391051-93-6)
- 3-Fluoroazetidine-2-carboxylic acid (CAS 36369-32-1)
- 3-Fluoroazetidine-3-carboxylic acid (CAS 1363380-85-1)
- (2Z)-2-[2-(2H-1,3-Benzodioxol-5-yl)-2-oxoethylidene]-3-oxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylic acid (CAS 904818-57-1)
- Methionylmethionine (CAS 52715-93-2)
- 5-(Trifluoromethyl)-1,2,3,4-tetrahydronaphthol (CAS 1202577-72-7)
- 2-Amino-2-(3-pyridyl)ethanol Dihydrochloride (CAS 1187930-70-6)
- 3-(4-(N,N-Dimethylsulfamoyl)phenyl)propiolic acid (CAS 1403566-01-7)
- Methyl 6-chloro-3-methylbenzo[b]thiophene-2-carboxylate (CAS 1415968-74-9)
- Hexa-2,4-dienedial (CAS 3249-28-3)
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- N-(tert-Butyl)-2-methylbut-3-yn-2-amine (CAS 1118-17-8)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
Why CATO?
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