Methyl (1S,5R)-5-amino-3,3-difluorocyclohexane-1-carboxylate hydrochloride CAS 2227198-08-3
| CAS No. | 2227198-08-3 |
| Molecular Formula | C8H13F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Methyl (1S,5R)-5-amino-3,3-difluorocyclohexane-1-carboxylate hydrochloride (CAS 2227198-08-3), a certified reference material (molecular formula C8H13F2NO2HCl, MW 229.65 g/mol) for analytical method development and quality control.
The molecular framework of Methyl (1S,5R)-5-amino-3,3-difluorocyclohexane-1-carboxylate hydrochloride (C8H13F2NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Methyl (1S,5R)-5-amino-3,3-difluorocyclohexane-1-carboxylate hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H13F2NO2 HCl |
| Molecular Weight | 229.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 6-(2-Bromophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine (CAS 1432680-41-5)
- 2-((2-((2-Fluorophenyl)sulfonamido)phenyl)thio)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 478045-38-4)
- 2,5-Dioxopyrrolidin-1-yl ((3R,3aS,6aR)-hexahydrofuro[2,3-B]furan-3-yl) carbonate (CAS 253265-97-3)
- 1'-(tert-Butoxycarbonyl)-4-oxospiro[chroman-2,4'-piperidine]-7-carboxylic acid (CAS 1086398-20-0)
- 2,4-Dimethoxybenzoic acid ethyl ester (CAS 81722-07-8)
- 4-Amino-2'-methoxy[1,1'-biphenyl]-3-carboxylic acid (CAS 893735-62-1)
- 2-(5-Methyl-3-nitro-1h-pyrazol-1-yl)butanehydrazide (CAS 1005668-98-3)
- 1-(3,5-Dimethyl-1H-pyrrol-2-yl)ethan-1-one (CAS 1500-93-2)
- 6-Amino-1-(pyridin-2-ylmethyl)pyrimidine-2,4(1H,3H)-dione (CAS 446266-75-7)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com