(2R,5R)-5-(fluoromethyl)-2-methylpiperidine CAS 2227198-72-1
| CAS No. | 2227198-72-1 |
| Molecular Formula | C7H14FN |
| Molecular Weight | 131.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2R,5R)-5-(fluoromethyl)-2-methylpiperidine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (2R,5R)-5-(fluoromethyl)-2-methylpiperidine (CAS 2227198-72-1), a certified reference material (molecular formula C7H14FN, MW 131.19 g/mol) for analytical method development and quality control.
The molecular framework of (2R,5R)-5-(fluoromethyl)-2-methylpiperidine (C7H14FN) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2R,5R)-5-(fluoromethyl)-2-methylpiperidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H14FN |
| Molecular Weight | 131.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (1S,4s)-4-fluoro-N-methylcyclohexan-1-amine (CAS 546085-46-5)
- (2S)-3-Fluoro-2-(2-methylpropyl)azetidine (CAS 2845282-03-1)
- ((1R,2S)-2-fluorocyclohexyl)methanamine (CAS 1903839-97-3)
- (2S,5R)-5-(fluoromethyl)-2-methylpiperidine (CAS 2306255-47-8)
- 2-Ethoxy-4-fluoroaniline (CAS 178993-28-7)
- 4-Hydroxy-3-methylbenzoyl chloride (CAS 1099832-26-4)
- 4-(3-Methyl-benzyl)-piperidine (CAS 496056-53-2)
- trans-2-(4-Butylphenyl)cyclohexanol (CAS 933674-50-1)
- N-(3-Chlorophenyl)-2,2,2-trifluoroacetamide (CAS 40410-54-6)
- (4-Fluoro-3-isopropylphenyl)methanamine (CAS 1245808-00-7)
- 4-[[(Dichlorofluoromethyl)Thio](Trifluoromethyl)Amino]Benzoic Acid (CAS 29363-53-9)
- Boc-Ser(Bzl)-OH.DCHA (CAS 10342-01-5)
- 2,4-Difluorobenzimidamide hydrochloride (CAS 1170536-00-1)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com