8-Chloro-5-methylpyrido[3,4-d]pyrimidin-4(3H)-one CAS 2227201-91-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Chloro-5-methylpyrido[3,4-d]pyrimidin-4(3H)-one.

8-Chloro-5-methylpyrido[3,4-d]pyrimidin-4(3H)-one (CAS 2227201-91-2) is a high-purity analytical reference standard with the molecular formula C8H6ClN3O and a molecular weight of 195.61 g/mol.

The molecular framework of 8-Chloro-5-methylpyrido[3,4-d]pyrimidin-4(3H)-one (C8H6ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 8-Chloro-5-methylpyrido[3,4-d]pyrimidin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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