Tert-butyl (2S)-4-cyano-2-methylpiperidine-1-carboxylate CAS 2227202-41-5
| CAS No. | 2227202-41-5 |
| Molecular Formula | C12H20N2O2 |
| Molecular Weight | 224.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tert-butyl (2S)-4-cyano-2-methylpiperidine-1-carboxylate (C12H20N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Tert-butyl (2S)-4-cyano-2-methylpiperidine-1-carboxylate (CAS 2227202-41-5), a certified reference material (molecular formula C12H20N2O2, MW 224.30 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl (2S)-4-cyano-2-methylpiperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H20N2O2 |
| Molecular Weight | 224.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (2R)-4-cyano-2-methylpiperidine-1-carboxylate (CAS 2306259-43-6)
- tert-butyl (3S)-3-cyanoazepane-1-carboxylate (CAS 2664977-68-6)
- SC-514, 99%, a selective IKK-2 inhibitor (CAS 354812-17-2)
- tert-Butyl (S)-2-(prop-2-yn-1-yl)piperazine-1-carboxylate (CAS 2700039-31-0)
- 5-Bromo-3-(2-methoxyethoxy)benzofuran-2-carboxylic acid (CAS 1707727-75-0)
- 3,5-difluoro-benzamidine hydrochloride (CAS 144797-68-2)
- 2-Methoxy-3-(4-nitrophenyl)pyridine (CAS 1352318-63-8)
- 2-(Cyano(1-methyl-1H-pyrrol-2-yl)methyl)-6-fluorobenzonitrile (CAS 303150-55-2)
- 2-Methoxy-3-(trifluoromethyl)cinnamic acid (CAS 1092460-72-4)
- 2-(4-Bromophenyl)-8-methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 524724-73-0)
- 2-[Benzyl(ethyl)amino]isonicotinic acid (CAS 1039979-57-1)
- 3-Ethoxyquinoxalin-2(1H)-one (CAS 860503-18-0)
- 5-(4-(2-Nitrophenyl)piperazin-1-yl)pyrrolidin-2-one (CAS 91703-27-4)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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