6-Azaspiro[2.5]Octane-5-carboxylic acid hydrochloride CAS 2227204-75-1
| CAS No. | 2227204-75-1 |
| Molecular Formula | C8H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Azaspiro[2.5]Octane-5-carboxylic acid hydrochloride (C8H13NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
6-Azaspiro[2.5]Octane-5-carboxylic acid hydrochloride (CAS 2227204-75-1) is a high-purity analytical reference standard with the molecular formula C8H13NO2HCl and a molecular weight of 191.66 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13NO2 HCl |
| Molecular Weight | 191.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Azaspiro Standards
- 2-Azaspiro[4.4]Nonan-1-one (CAS 1004-51-9)
- 2-Azaspiro[4.5]decan-1-one (CAS 1005-85-2)
- 2-(3-Azaspiro[5.5]Undecan-3-yl)ethan-1-amine (CAS 1012-58-4)
- 1-Oxa-2-azaspiro[4.5]dec-2-ene-3-carboxylicacid (CAS 1015770-72-5)
- Methyl 2-{3-azaspiro[5.5]undecan-9-yl}acetate hydrochloride (CAS 1017540-91-8)
- Methyl 2-(3-azaspiro[5.5]Undecan-9-yl)acetate (CAS 1017623-70-9)
- 3-Benzyl-3-azaspiro[bicyclo[3.2.1]octane-8,2'-[1,3]dioxolane] (CAS 1019208-04-8)
- Benzyl 6-azaspiro[2.5]octane-6-carboxylate (CAS 1037834-61-9)
Recommended Standards
- 1-(2-Chloro-5-(trifluoromethyl)phenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrole (CAS 338749-72-7)
- Methyl 3-(benzo[d]thiazol-2-yl)propanoate (CAS 610277-15-1)
- (4-Methoxy-benzothiazol-2-yl)-hydrazine (CAS 53065-23-9)
- 1-[(bromomethyl)sulfonyl]-4-methylbenzene (CAS 37891-95-5)
- (2E)-4-(Biphenyl-2-ylamino)-4-oxobut-2-enoic acid (CAS 1164564-94-6)
- 3-Hydroxy Valproic Acid (Mixture of Diastereomers) (CAS 58888-84-9)
- (2-(Piperazin-1-yl)pyridin-3-yl)boronic acid dihydrochloride (CAS 2096336-81-9)
- 2',3'-Dithiouridine (CAS 156592-92-6)
- 5-Methyl-2-(2-(trifluoromethyl)phenyl)thiazole-4-carboxylic acid (CAS 1549437-07-1)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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