1-Benzyl-3,3-difluoro-1,8-diazaspiro[4.5]decane dihydrochloride CAS 2227205-10-7
| CAS No. | 2227205-10-7 |
| Molecular Formula | C15H20F2N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Benzyl-3,3-difluoro-1,8-diazaspiro[4.5]decane dihydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Benzyl-3,3-difluoro-1,8-diazaspiro[4.5]decane dihydrochloride (CAS 2227205-10-7) is a high-purity analytical reference standard with the molecular formula C15H20F2N2HCl and a molecular weight of 302.79 g/mol.
The molecular framework of 1-Benzyl-3,3-difluoro-1,8-diazaspiro[4.5]decane dihydrochloride (C15H20F2N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Benzyl-3,3-difluoro-1,8-diazaspiro[4.5]decane dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20F2N2 2*HCl |
| Molecular Weight | 302.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Benzyl Standards
- 2-(4,5-Difluoro-2-nitrophenyl)acetic acid (CAS 1000339-22-9)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]piperazine (CAS 1000339-47-8)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]homopiperazine (CAS 1000339-49-0)
- 4,7-Difluoro-1H-indazole (CAS 1000341-68-3)
- 5,7-Difluoro-2H-indazole-3-carbaldehyde (CAS 1000343-25-8)
- 6,7-Difluoro-1H-indazol-3-ol (CAS 1000343-93-0)
- 2-(3,5-Difluoro-2-pyridyl)acetic acid (CAS 1000518-01-3)
- 2-(2,4-Difluoro-3-methylphenyl)acetic acid (CAS 1000545-11-8)
Recommended Standards
- (S)-1-(5-Bromofuran-2-yl)ethan-1-ol (CAS 1425938-19-7)
- 9-Hexyl-3,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 628336-95-8)
- 3-(Methylamino)pyridine (CAS 18364-47-1)
- 2-(2,5,6-Trichloropyridin-3-yl)acetic acid (CAS 63580-09-6)
- 2-Isopropylquinazolin-4-ol (CAS 13182-64-4)
- 2-Phenylpyrimidine-4,6-diol (CAS 13566-71-7)
- (3R,4S)-4-(6-methoxypyridin-3-yl)pyrrolidine-3-carboxylic acid (CAS 1392266-65-7)
- 2-(2-Ethoxyethoxy)acetaldehyde (CAS 125117-60-4)
- tert-Butyl 2-(hydroxymethyl)benzyl(methyl)carbamate (CAS 1823520-56-4)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com