Tert-butyl 7-fluoro-2-azaspiro[4.4]Nonane-2-carboxylate CAS 2227205-37-8
| CAS No. | 2227205-37-8 |
| Molecular Formula | C13H22FNO2 |
| Molecular Weight | 243.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tert-butyl 7-fluoro-2-azaspiro[4.4]Nonane-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tert-butyl 7-fluoro-2-azaspiro[4.4]Nonane-2-carboxylate (CAS 2227205-37-8), molecular formula C13H22FNO2 and molecular weight 243.32 g/mol, is a CATO reference standard with documented purity and traceability.
Tert-butyl 7-fluoro-2-azaspiro[4.4]Nonane-2-carboxylate (C13H22FNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H22FNO2 |
| Molecular Weight | 243.32 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl 3-allyl-3-fluoropiperidine-1-carboxylate (CAS 2168992-19-4)
- Tert-butyl 8-oxo-5-thia-2-azaspiro[3.4]Octane-2-carboxylate (CAS 2166784-06-9)
- S-Pyridin-2-yl 3-phenylpropanethioate (CAS 43125-15-1)
- tert-butyl N-[4-(methoxymethyl)thiophen-2-yl]carbamate (CAS 1989659-38-2)
- 2-Hydrazinyl-3-methylpyrazine (CAS 19848-54-5)
- N-(4-Fluoro-2-hydroxy-5-nitrophenyl)acetamide (CAS 137589-57-2)
- 2-((4-Chlorophenyl)thio)-N-(2,5-dimethyl-1H-pyrrol-1-yl)acetamide (CAS 75129-73-6)
- 2,2-Dimethyl-6-nitro-chromane (CAS 19989-17-4)
- Phellodendrine (CAS 6873-13-8)
- 5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(6H)-thione (CAS 94341-98-7)
- 3-Bromo-5-chloro-2-fluoroaniline hydrochloride (CAS 1384265-18-2)
- (4-Ethylthiazol-2-yl)methanamine (CAS 936940-69-1)
- Europium(III) chloride hexahydrate (CAS 13759-92-7)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com