4-Chloro-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one CAS 2227205-65-2
| CAS No. | 2227205-65-2 |
| Molecular Formula | C7H6ClN3O |
| Molecular Weight | 183.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one (CAS 2227205-65-2), molecular formula C7H6ClN3O and molecular weight 183.60 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-Chloro-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3O |
| Molecular Weight | 183.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 100367-42-8)
- 4-Chloro-3,6-dimethylisoxazolo[5,4-d]pyrimidine (CAS 1023758-00-0)
- (6-Chloro-7H-purin-8-yl)methanamine (CAS 1044770-59-3)
- 7-Chloro-5-methoxy-1H-benzo[d][1,2,3]triazole (CAS 1086836-89-6)
- 6-Chloro-3-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one (CAS 120422-89-1)
- 2-Chloro-8-methoxy-[1,2,4]triazolo[1,5-a]pyridine (CAS 1207970-17-9)
- 4-Chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one (CAS 1226804-06-3)
- 2-Chloro-4-hydrazinyl-5H-pyrrolo[2,3-d]pyrimidine (CAS 1260667-61-5)
Recommended Standards
- 4-Chloro-6-methoxy-2-methylpyrimidine-5-carbonitrile (CAS 875233-60-6)
- 4H-Pyrazolo[5,1-c][1,4]oxazine-6-carbonitrile, 3-chloro-6,7-dihydro- (CAS 2121711-49-5)
- 4-Chloro-6,7-dihydropyrido[3,4-d]pyrimidin-8(5H)-one (CAS 2227205-61-8)
- 5-Amino-4-chloro-1H-benzo[d]imidazol-2(3H)-one (CAS 72735-26-3)
- Potassium trifluoro(1H-indol-6-yl)borate (CAS 1111733-01-7)
- 2-(Quinolin-4-yloxy)ethan-1-amine (CAS 34256-23-0)
- Taurine (CAS 107-35-7)
- Bis(m-Chlorophenyl) sulfone (CAS 5097-16-5)
- 5-propylfuran-2-carboxylic acid (CAS 14497-25-7)
- (E)-3-(4-Chlorophenyl)prop-2-en-1-amine (CAS 60691-88-5)
- tert-Butyl (3-hydroxycyclohexyl)(methyl)carbamate (CAS 1332632-81-1)
- (4-(Trifluoromethoxy)phenyl)zinc bromide, 0.50 M in THF (CAS 2097808-42-7)
- (R)-phenyl(piperidin-4-yl)methanol (CAS 957202-23-2)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
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