1-(5-methylpyrazin-2-yl)methanamine dihydrochloride CAS 2227206-03-1
| CAS No. | 2227206-03-1 |
| Molecular Formula | C6H15N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(5-methylpyrazin-2-yl)methanamine dihydrochloride is closely related to chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(5-methylpyrazin-2-yl)methanamine dihydrochloride (CAS 2227206-03-1), molecular formula C6H15N3HCl and molecular weight 165.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-methylpyrazin-2-yl)methanamine dihydrochloride (C6H15N3HCl) is characterized by chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H15N3 2*HCl |
| Molecular Weight | 165.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related methylpyrazin Standards
- 1-(3-methylpyrazin-2-yl)ethan-1-amine (CAS 1027763-60-5)
- 2-(((5-Methylpyrazin-2-yl)methyl)amino)ethanethiol (CAS 105827-86-9)
- 2-((5-Methylpyrazin-2-yl)amino)ethanethiol (CAS 105954-48-1)
- O-((5-Methylpyrazin-2-yl)methyl)hydroxylamine (CAS 1091680-97-5)
- 2-[4-(3-Methylpyrazin-2-yl)phenyl]-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide (CAS 1146395-46-1)
- (R)-1-(5-METHYLPYRAZIN-2-YL)ETHAN-1-AMINE HCL (CAS 1147379-19-8)
- 5-Methylpyrazin-2-amine hydrochloride (CAS 1159824-25-5)
- (5-Methylpyrazin-2-yl)methanesulfonyl chloride (CAS 1196146-13-0)
Recommended Standards
- methyl 2-chloropyrimidine-5-carboxylate (CAS 287714-35-6)
- 3,5-difluoro-2-hydroxybenzene-1-sulfonyl chloride (CAS 165661-51-8)
- Diethyl 2-(((3-chloro-2-methylphenyl)amino)methylene)malonate (CAS 58666-10-7)
- 4,6-Dichloro-N-methylpyridazine-3-carboxamide (CAS 1609394-78-6)
- (S)-2-Amino-N-(4-(N-ethylacetamido)cyclohexyl)-3-methylbutanamide (CAS 1354003-45-4)
- 1-(Benzyloxy)-2-chloro-4,5-difluorobenzene (CAS 2624417-62-3)
- Milrinone impurity 38 (CAS CATO-C4X-109138)
- Bicyclo[2.1.1]Hexan-1-ylmethanol (CAS 90049-44-8)
- 1016790-80-9 N-(3-Amino-4-methylphenyl)-2-phenylacetamide (CAS 1016790-80-9)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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