Tert-butyl 6-fluoro-2-azabicyclo[2.2.2]Octane-2-carboxylate CAS 2227206-32-6

Purity 97%+In StockPharmaceutical Standards
CAS No.2227206-32-6
Molecular FormulaC12H20FNO2
Molecular Weight229.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl 6-fluoro-2-azabicyclo[2.2.2]Octane-2-carboxylate CAS 2227206-32-6 chemical structure

Description

The occurrence of Tert-butyl 6-fluoro-2-azabicyclo[2.2.2]Octane-2-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Tert-butyl 6-fluoro-2-azabicyclo[2.2.2]Octane-2-carboxylate (CAS 2227206-32-6), a certified reference material (molecular formula C12H20FNO2, MW 229.29 g/mol) for analytical method development and quality control.

The molecular framework of Tert-butyl 6-fluoro-2-azabicyclo[2.2.2]Octane-2-carboxylate (C12H20FNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Tert-butyl 6-fluoro-2-azabicyclo[2.2.2]Octane-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H20FNO2
Molecular Weight229.29 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF-containing
Nitrogen Atoms1

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