1-(Pyrimidin-5-yl)azetidin-3-amine dihydrochloride CAS 2227206-48-4
| CAS No. | 2227206-48-4 |
| Molecular Formula | C7H10N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(Pyrimidin-5-yl)azetidin-3-amine dihydrochloride is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(Pyrimidin-5-yl)azetidin-3-amine dihydrochloride (CAS 2227206-48-4), a certified reference material (molecular formula C7H10N4HCl, MW 186.64 g/mol) for analytical method development and quality control.
1-(Pyrimidin-5-yl)azetidin-3-amine dihydrochloride (C7H10N4HCl) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Pyrimidin-5-yl)azetidin-3-amine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10N4 2*HCl |
| Molecular Weight | 186.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Pyrimidin Standards
- 2-(Pyrimidin-5-yl)acetonitrile (CAS 1000564-45-3)
- (4-(Pyrimidin-2-yl)phenyl)methanol (CAS 100806-78-8)
- 1-(Pyrimidin-2-yl)pyrrolidine-2-carboxylic acid (CAS 1009282-26-1)
- (Pyrimidin-2-yl)phosphonic acid (CAS 101257-34-5)
- (Pyrimidin-2-ylmethyl)glycine (CAS 1013025-61-0)
- 2-(Pyrimidin-2-yl)-1,3-thiazole-5-carboxylic acid (CAS 1014630-98-8)
- 2-(pyrimidin-2-yl)-1,3-thiazole-4-carboxylic acid (CAS 1014631-26-5)
- 1-(Pyrimidin-2-yl)-1h-pyrazole-3-carboxylic acid (CAS 1014631-78-7)
Recommended Standards
- 5-Methoxy-2-methylthieno[2,3-e][1,3]benzothiazole (CAS 313953-19-4)
- Imidazo[1,2-a]pyridin-2-ylmethyl morpholine-4-carbodithioate (CAS 380351-79-1)
- 3-(2,6-Dichlorophenyl)propanal (CAS 1057670-91-3)
- 1-methyl-2-(1-methyl-1H-imidazol-2-yl)piperazine (CAS 1369243-65-1)
- Methyl 4-chlorothieno[3,2-d]pyrimidine-2-carboxylate (CAS 1379302-45-0)
- 6-Methyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 1279204-24-8)
- 8-(Bromomethyl)-2,3-dimethyl-7,8-dihydro-4H-thiazolo[3,2-a]thieno[3,2-e]pyrimidin-4-one (CAS 284687-86-1)
- Ethyl 3-(5-(2,4-dichlorophenyl)furan-2-yl)acrylate (CAS 886496-73-7)
- 4H-benzo[d][1,3]dioxin-6-amine (CAS 22791-64-6)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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