7-bromo-N-(1,3-dimethylpyrazol-4-yl)quinazolin-2-amine CAS 2227206-75-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-bromo-N-(1,3-dimethylpyrazol-4-yl)quinazolin-2-amine.

7-bromo-N-(1,3-dimethylpyrazol-4-yl)quinazolin-2-amine (CAS 2227206-75-7), molecular formula C13H26BrN5 and molecular weight 332.28 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, bromine substitution, 7-bromo-N-(1,3-dimethylpyrazol-4-yl)quinazolin-2-amine is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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