Diethyl 2-(3-oxocyclohexyl)malonate CAS 22274-75-5
| CAS No. | 22274-75-5 |
| Molecular Formula | C13H20O5 |
| Molecular Weight | 256.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Diethyl 2-(3-oxocyclohexyl)malonate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Diethyl 2-(3-oxocyclohexyl)malonate (CAS 22274-75-5) is a high-purity analytical reference standard with the molecular formula C13H20O5 and a molecular weight of 256.29 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Diethyl 2-(3-oxocyclohexyl)malonate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 256.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Diethyl 2-(3-oxocyclohexyl)malonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H20O5 |
| Molecular Weight | 256.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
Related Diethyl Standards
- Diethyl 2-(2-oxocyclohexyl)malonate (CAS 4039-31-0)
- Diethyl 4,5-dimethylpyridazine-1,2(3H,6H)-dicarboxylate (CAS 7249-39-0)
- Diethyl [(2,6-dimethylphenyl)methyl]phosphonate (CAS 902526-55-0)
- Diethyl (1,3-dithian-2-yl)phosphonate (CAS 62999-73-9)
- Diethyl 2-(thiophen-2-ylmethyl)malonate (CAS 26420-00-8)
- Diethyl 2,5-dihydroxycyclohexa-1,4-diene-1,4-dicarboxylate (CAS 16877-79-5)
- Diethyl 4-formylbenzylphosphonate (CAS 125185-25-3)
- Diethyl 2-(5-fluoropyrimidin-4-yl)malonate (CAS 1333169-66-6)
Recommended Standards
- Ethyl 8-acetyl-1,4-dioxaspiro[4.5]decane-8-carboxylate (CAS 2143552-99-0)
- Acetoxy(tetrahydrofuran-2-yl)methyl cyclopentanecarboxylate (CAS 6946-60-7)
- Methyl 1,4,9-trioxadispiro[4.2.48.25]tetradecane-10-carboxylate (CAS 2177266-33-8)
- 2-(1-(3,4-Difluorobenzyl)piperazin-2-yl)ethan-1-ol (CAS 815603-03-3)
- 5-Cyano-2-hydroxypyrimidine (CAS 1753-49-7)
- 2-(2-(Trimethylsilyl)ethyl)-1,3,6,2-dioxazaborocane (CAS 501014-43-3)
- 2-Fluoro-2-phenylcyclopropane-1-carboxylic acid (CAS 914221-42-4)
- 1-(4-Acetylphenyl)-2-Methyl-1-Propanone (CAS 103931-20-0)
- 1-(5-bromo-3-methoxypyridin-2-yl)ethan-1-one (CAS 1211521-17-3)
- Venetoclax Impurity 24 (CAS CATO-C4X-249524)
- 1,4-Dibromo-2,5-bis[2-(trimethylsilyl)ethynyl]benzene (CAS 478190-79-3)
- 3-Bromo-1H-pyrrolo[2,3-b]pyridin-4-ol (CAS 1190322-34-9)
- 2-(tert-Butyl)-5-chloropyrimidine (CAS 91167-21-4)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
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