4,6-Di(1H-1,2,4-triazol-1-yl)isophthalic acid CAS 2227468-63-3
| CAS No. | 2227468-63-3 |
| Molecular Formula | C12H8N6O4 |
| Molecular Weight | 300.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,6-Di(1H-1,2,4-triazol-1-yl)isophthalic acid.
CATO supplies 4,6-Di(1H-1,2,4-triazol-1-yl)isophthalic acid (CAS 2227468-63-3), a certified reference material (molecular formula C12H8N6O4, MW 300.23 g/mol) for analytical method development and quality control.
The molecular framework of 4,6-Di(1H-1,2,4-triazol-1-yl)isophthalic acid (C12H8N6O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8N6O4 |
| Molecular Weight | 300.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 6 |
Recommended Standards
- 3-azido-6-(2,6-dioxo-3-piperidyl)pyrrolo[3,4-b]pyridine-5,7-dione (CAS 2913370-52-0)
- 4,6-Dimethoxy-2-[3-(trifluoromethyl)phenoxy]pyrimidine (CAS 294848-95-6)
- 2,5-Di(1H-1,2,4-triazol-1-yl)terephthalic acid (CAS 2163052-04-6)
- 4-Methoxyphenyl 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 320423-21-0)
- 3-(2-Methyl-1H-imidazol-1-yl)propan-1-ol (CAS 22159-27-9)
- (S)-2-Amino-3-(2,6-dihydroxyphenyl)propanoic acid (CAS 552289-20-0)
- 4-Methyl-2-(4-methylpiperidin-1-yl)pyrimidine-5-carboxylic acid (CAS 924867-94-7)
- 1-Isopropyl-6-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid (CAS 1781301-83-4)
- 4-(3-(Benzyloxy)benzylidene)-2-phenyloxazol-5(4H)-one (CAS 113697-04-4)
- 5,6-Di(pyridin-2-yl)-2,3-dihydropyrazine (CAS 25005-95-2)
- 5-Chloro-2-phenyl-1,3-oxazole-4-carboxamide (CAS 855841-14-4)
- 4-(1H-Pyrazole-4-yl)benzaldehyde (CAS 1017794-45-4)
- 2-Chloro-n-[(4-sulfamoylphenyl)methyl]acetamide (CAS 101167-02-6)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
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