4-Amino-5-bromo-1H-pyrrolo[2,3-d]pyrimidine CAS 22276-99-9
| CAS No. | 22276-99-9 |
| Molecular Formula | C6H5BrN4 |
| Molecular Weight | 213.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Amino-5-bromo-1H-pyrrolo[2,3-d]pyrimidine (CAS 22276-99-9), a certified reference material (molecular formula C6H5BrN4, MW 213.03 g/mol) for analytical method development and quality control.
Structurally, 4-Amino-5-bromo-1H-pyrrolo[2,3-d]pyrimidine (C6H5BrN4) contains a nitrile group, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 213.03 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5BrN4 |
| Molecular Weight | 213.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-Amino-5-bromo-[1,2,4]triazolo[1,5-a]pyridine (CAS 1010120-55-4)
- 8-Amino-6-bromoimidazo[1,2-a]pyrazine (CAS 117718-84-0)
- 8-Amino-3-bromoimidazo[1,2-a]pyrazine (CAS 117718-92-0)
- 2-Amino-7-bromobenzoxazole (CAS 1211527-07-9)
- 2-Amino-6-bromo-3H-imidazo[4,5-b]pyridine (CAS 1250115-39-9)
- 3-Amino-6-bromo-[1,2,4]triazolo[4,3-a]pyridine (CAS 1378862-01-1)
- 3-Amino-6-bromo-5-methylpyrazine-2-carbonitrile (CAS 160602-31-3)
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Recommended Standards
- 4-Amino-3-bromofuro[3,2-c]pyridine (CAS 799293-73-5)
- 4-Bromo-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one (CAS 913393-94-9)
- 4-Amino-2-bromo-3-hydroxybenzonitrile (CAS 676124-40-6)
- 4-Bromo-1H-indazol-3(2H)-one (CAS 864845-15-8)
- 1-(Benzo[d]thiazol-2-ylthio)butan-2-one (CAS 244221-70-3)
- (E)-3-(2-Methoxy-5-methylphenyl)acrylaldehyde (CAS 889135-71-1)
- 3-(Ethylthio)-5-methyl-1H-1,2,4-triazole (CAS 126909-98-6)
- 3-(2-Fluorophenyl)propionic acid (CAS 1643-26-1)
- 4-(Difluoromethyl)-2-ethyl-3-methyl-2h-pyrazolo[3,4-b]pyridin-6-ol (CAS 1018126-34-5)
- 1,4-Diamino-2-butoxy-7-chloroanthracene-9,10-dione (CAS 88605-48-5)
- 3-(pyrrolidin-2-yl)oxan-4-ol (CAS 1559310-25-6)
- 1-Ethynyl-2,5-difluoro-4-methoxybenzene (CAS 1233509-71-1)
- Methyl 2-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1638768-39-4)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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