Tert-butyl4-[(1s)-2,2,2-trifluoro-1-hydroxy-ethyl]piperidine-1-carboxylate CAS 2227693-01-6
| CAS No. | 2227693-01-6 |
| Molecular Formula | C12H20F3NO3 |
| Molecular Weight | 283.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tert-butyl4-[(1s)-2,2,2-trifluoro-1-hydroxy-ethyl]piperidine-1-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tert-butyl4-[(1s)-2,2,2-trifluoro-1-hydroxy-ethyl]piperidine-1-carboxylate (CAS 2227693-01-6), molecular formula C12H20F3NO3 and molecular weight 283.29 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H20F3NO3, Tert-butyl4-[(1s)-2,2,2-trifluoro-1-hydroxy-ethyl]piperidine-1-carboxylate contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 283.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20F3NO3 |
| Molecular Weight | 283.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (R)-4-(2,2,2-trifluoro-1-hydroxyethyl)piperidine-1-carboxylate (CAS 2227681-07-2)
- 4-Amino-N-(4,5-dimethylisoxazol-3-yl)-3-hydroxybenzenesulfonamide (CAS 105553-27-3)
- Sec-Butyl N-(Trifluoroacetyl)Norleucinate (CAS 57983-76-3)
- 3-[(2-Oxo-1,2,3,4-tetrahydroquinolin-6-yl)-sulfonyl]propanoic acid (CAS 1119451-25-0)
- 1-(3-Amino-2,6-dimethylphenyl)pyrrolidin-2-one (CAS 69131-45-9)
- N-(4-Methoxyphenyl)-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide (CAS 298215-19-7)
- 2-((3,5-Dimethoxybenzyl)thio)-5-(4-methylpiperazin-1-yl)-1,3,4-thiadiazole (CAS 1105220-89-0)
- 2-Oxa-8-azaspiro[4.5]decan-1-one (CAS 4427-25-2)
- Hydroxy Saxagliptin-15N,D2 Hydrochloride (CAS 1309934-05-1)
- 6-(2-Fluorophenyl)-2-methylpyrimidin-4-amine (CAS 1159819-61-0)
- tert-Butyl 3-{[(oxolan-2-yl)methyl]amino}propanoate (CAS 1049155-73-8)
- 3-Cyclopropoxy-5-(dimethylamino)benzenesulfonamide (CAS 1243465-75-9)
- 2-Bromo-4,5-difluorobenzenethiol (CAS 1263376-26-6)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com