6-Chloro-2-(chloromethyl)-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one CAS 22280-91-7
| CAS No. | 22280-91-7 |
| Molecular Formula | C16H12Cl2N2O |
| Molecular Weight | 319.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Chloro-2-(chloromethyl)-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one (CAS 22280-91-7), a certified reference material (molecular formula C16H12Cl2N2O, MW 319.19 g/mol) for analytical method development and quality control.
Structurally, 6-Chloro-2-(chloromethyl)-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one (C16H12Cl2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 319.19 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Chloro-2-(chloromethyl)-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl2N2O |
| Molecular Weight | 319.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-N-((5-(3-chlorophenyl)-1H-1,2,4-triazol-3-yl)methyl)aniline (CAS 1171939-54-0)
- [5-Chloro-3-(4-chloro-phenyl)-1-phenyl-1H-pyrazol-4-yl]-methanol (CAS 55828-93-8)
- 3-(4-Chloro-2-methylphenyl)-2-(chloromethyl)-3,4-dihydroquinazolin-4-one (CAS 69123-64-4)
- 7-Chloro-5-(2-chlorophenyl)-2-hydrazinyl-3H-1,4-benzodiazepine (1.0mg/ml in Acetonitrile) (CAS 40070-48-2)
- 2-chloro-N-(4-chlorophenyl)-1-methyl-1H-indole-3-carboxamide 478049-45-5 KS-000039VU (CAS 478049-45-5)
- 2-Chloro-1-[6-(2-chloro-acetyl)-9H-fluoren-3-yl]-ethanone (CAS 726156-98-5)
- 4-(4-Chloro-6-methyl-pyrimidin-2-yloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (CAS 1289388-10-8)
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Recommended Standards
- 6,8-Dichloro-3-(4-methylbenzyl)quinazolin-4(3H)-one (CAS 302913-35-5)
- 6-(Bis(phosphonomethyl)amino)hexanoic acid (CAS 55628-97-2)
- 4'-Benzyloxy-2-bromopropiophenone (CAS 35081-45-9)
- 4'-carboethoxy-3-(3-methoxyphenyl)propiophenone (CAS 898774-84-0)
- 6-Bromo-2-(difluoromethyl)-5-nitropyridin-3-ol (CAS 1806835-05-1)
- 6,7-Dichloropyrido[2,3-d]pyrimidin-4(3H)-one (CAS 2820180-24-1)
- Ethyl 4-(1-((tert-butoxycarbonyl)amino)cyclopropyl)pyrrolidine-3-carboxylate (CAS 1373028-31-9)
- 1,2-Bis(thiophen-2-yl)ethan-1-one (CAS 53119-26-9)
- 3’-Demethylnobiletin (CAS 112448-39-2)
- 2-((1-Methyl-1H-indol-3-yl)methyl)malononitrile (CAS 771562-50-6)
- 1-[2-(Diallylamino)-ethyl]-piperazine (CAS 199475-35-9)
- 1-(2-(6-Bromopyridin-3-yl)piperidin-1-yl)ethanone (CAS 1352492-67-1)
- 3-bromo-1H-pyrazolo[3,4-b]pyrazine (CAS 81411-68-9)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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