2-Iodo-4-methylpyridine CAS 22282-60-6
| CAS No. | 22282-60-6 |
| Molecular Formula | C6H6IN |
| Molecular Weight | 219.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Iodo-4-methylpyridine (CAS 22282-60-6), molecular formula C6H6IN and molecular weight 219.02 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H6IN, 2-Iodo-4-methylpyridine contains a nitrile group, iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 219.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6IN |
| Molecular Weight | 219.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 3-Iodo-2-methylpyridine (CAS 15112-62-6)
- 3-Iodo-5-methylpyridine (CAS 15366-64-0)
- 2-Iodo-5-methylpyridine (CAS 22282-62-8)
- 2-Iodo-6-methylpyridine (CAS 62674-71-9)
- 3-Iodo-4-methylpyridine (CAS 38749-96-1)
- 4-Iodo-2-methylpyridine (CAS 22282-65-1)
- 4-Iodo-3-methylpyridine (CAS 22282-64-0)
- 5-Iodo-2-methylpyridine (CAS 695-17-0)
Recommended Standards
- 2-(Iodomethyl)pyridine (CAS 929876-97-1)
- 2-(3,4-Dichlorophenyl)-2-oxoacetic acid (CAS 64471-83-6)
- 2-(2,5-Dichlorophenyl)-2-oxoacetic acid (CAS 26767-05-5)
- 3-(1-Cyanocyclobutyl)-2-fluorophenylboronic acid (CAS 2096330-05-9)
- 2-(Difluoromethyl)-m-xylene (CAS 1214358-11-8)
- 2-(Quinolin-5-ylamino)-1,3-thiazole-4-carboxylic acid (CAS 1189749-55-0)
- 6-tert-butylpyridine-3-carboximidamide (CAS 1211532-61-4)
- 1-Amino-3-(1,3-dioxaindan-5-yloxy)propan-2-ol (CAS 258853-83-7)
- 2,2-Dimethyl-3-(morpholin-4-ylcarbonyl)-cyclopropanecarboxylic acid (CAS 167113-75-9)
- Relebactam Impurity 40 (CAS CATO-C4X-214440)
- (3S)-3-aminoazetidin-2-one hydrochloride (CAS 2044711-48-8)
- Methyl 2-(6-bromo-4-chloropyridin-2-yl)acetate (CAS 1805486-16-1)
- 4-(Azepan-1-yl)-3-methylaniline (CAS 1094646-23-7)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
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