2-(1H-indol-5-yl)-2-methylpropanoic acid CAS 2228206-54-8

Purity 97%+In StockPharmaceutical Standards
CAS No.2228206-54-8
Molecular FormulaC12H13NO2
Molecular Weight203.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(1H-indol-5-yl)-2-methylpropanoic acid CAS 2228206-54-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 203.24 g/mol gives 2-(1H-indol-5-yl)-2-methylpropanoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(1H-indol-5-yl)-2-methylpropanoic acid (CAS 2228206-54-8) is a high-purity analytical reference standard with the molecular formula C12H13NO2 and a molecular weight of 203.24 g/mol.

2-(1H-indol-5-yl)-2-methylpropanoic acid (C12H13NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(1H-indol-5-yl)-2-methylpropanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H13NO2
Molecular Weight203.24 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Nitrogen Atoms1

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