4-Ethynyl-2-methoxy-1-(trifluoromethyl)benzene CAS 2228650-14-2
| CAS No. | 2228650-14-2 |
| Molecular Formula | C10H7F3O |
| Molecular Weight | 200.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Ethynyl-2-methoxy-1-(trifluoromethyl)benzene (CAS 2228650-14-2), a certified reference material (molecular formula C10H7F3O, MW 200.16 g/mol) for analytical method development and quality control.
4-Ethynyl-2-methoxy-1-(trifluoromethyl)benzene (C10H7F3O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Ethynyl-2-methoxy-1-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F3O |
| Molecular Weight | 200.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Ethynyl Standards
- 2-Ethynyl-1-methoxy-4-(trifluoromethyl)benzene (CAS 1211587-48-2)
- 1-Ethynyl-4-(2,2,2-trifluoroethoxy)benzene (CAS 1823504-62-6)
- 1-Ethynyl-2-methyl-4-(trifluoromethoxy)benzene (CAS 2503208-09-9)
- 1-Ethynyl-3-methoxy-5-(trifluoromethyl)benzene (CAS 2307299-85-8)
- 1-Ethynyl-4-methoxy-2-(trifluoromethyl)benzene (CAS 2229518-36-7)
- 4-Ethynyl-1-(4-fluorophenyl)-2-methyl-1H-imidazole (CAS 761426-56-6)
- 1-Ethynyl-4-phenylcyclohexan-1-ol (CAS 29071-43-0)
- 1-Ethynyl-4-heptylbenzene (CAS 79887-12-0)
Recommended Standards
- 4-amino-5-methyl-2-(trifluoromethyl)benzonitrile (CAS 875056-26-1)
- 4-Methyl-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 6742-83-2)
- 4-Amino-3-methyl-2-(trifluoromethyl)benzonitrile (CAS 573764-86-0)
- 5-(Methoxy-d3)-2-nitrobenzoic acid (CAS 2098655-64-0)
- 3-Phenyl-2-(thiophene-2-carboxamido)propanoic acid (CAS 381214-41-1)
- 3-Chloro-n-cyclopropyl-n-(4-methoxybenzyl)benzenesulfonamide (CAS 1043344-89-3)
- 1-Phenyl-3-(4H-1,2,4-triazol-4-yl)thiourea (CAS 5102-30-7)
- Dimethyl 2-(4-bromobenzyl)malonate (CAS 157134-36-6)
- 4-Chloro-N-(piperidin-4-yl)pyrimidin-2-amine hydrochloride (CAS 1185310-78-4)
- Nω-Nitro-L-arginine (CAS 2149-70-4)
- 3-Bromo-4-chloro-5-methoxyaniline (CAS 940948-33-4)
- 2,3,4,9-Tetrahydro-1H-carbazol-1-one O-hexanoyl oxime (CAS 860612-26-6)
- Avanafil Impurity N91 (CAS 31519-62-7)
- Peptide 441 (CAS CATO-CPTD788441)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com