DBCO-PEG1-NHS ester CAS 2228857-34-7
| CAS No. | 2228857-34-7 |
| Molecular Formula | C28H27N3O7 |
| Molecular Weight | 517.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of DBCO-PEG1-NHS ester is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
DBCO-PEG1-NHS ester (CAS 2228857-34-7) is a high-purity analytical reference standard with the molecular formula C28H27N3O7 and a molecular weight of 517.53 g/mol.
The molecular framework of DBCO-PEG1-NHS ester (C28H27N3O7) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), DBCO-PEG1-NHS ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H27N3O7 |
| Molecular Weight | 517.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
Related DBCO Standards
- DBCO-NHCO-PEG4-amine (CAS 1255942-08-5)
- DBCO-PEG4-amine (CAS 1840886-10-3)
- DBCO-PEG4-alcohol (CAS 1416711-60-8)
- DBCO-Sulfo-NHS ester (sodium) (CAS 1400191-52-7)
- DBCO-PEG2-NH-Boc (CAS 2377004-08-3)
- DBCO-PEG1-NH-Boc (CAS 2364591-77-3)
- DBCO-C2-SulfoNHS ester (CAS 1803279-86-8)
- Dbco-peg4-acid (CAS 2110448-99-0)
Recommended Standards
- 7-[4-[(2,3-Dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1-piperazinyl]-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (CAS 743444-68-0)
- Naltrexone-3-β-D-glucuronide (CAS 76630-71-2)
- 3-(5-(4-(Cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxybenzo-[d]isoxazol-6-yl)methoxy)phenyl)propanoic acid (CAS 530141-72-1)
- Rimegepant Impurity 34 (CAS CATO-C4X-248734)
- 4-(Methylsulfanyl)-2-(2-phenoxyacetamido)butanoic acid (CAS 882656-30-6)
- 1H,2H,3H-thieno[2,3-d]imidazol-2-one (CAS 71309-43-8)
- tert-Butyl (1R,4R,5R)-5-amino-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 1400808-02-7)
- 4-Methylpentanethioamide (CAS 16525-32-9)
- 1-(Bromomethyl)-4-(1,1,1-trifluoropropan-2-yl)benzene (CAS 1204295-85-1)
- N-methylspiro[3.4]Octan-2-amine (CAS 1527683-05-1)
- 3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid (CAS 352454-15-0)
- 5-(Pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 371758-70-2)
- (3R,8AR)-3-methylhexahydropyrrolo[1,2-a]pyrazin-4(1H)-one hydrochloride (CAS 2230901-06-9)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
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