2-Bromo-6-ethynylphenol CAS 2229152-00-3
| CAS No. | 2229152-00-3 |
| Molecular Formula | C8H5BrO |
| Molecular Weight | 197.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-6-ethynylphenol.
2-Bromo-6-ethynylphenol (CAS 2229152-00-3) is a high-purity analytical reference standard with the molecular formula C8H5BrO and a molecular weight of 197.03 g/mol.
The molecular framework of 2-Bromo-6-ethynylphenol (C8H5BrO) is characterized by a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-6-ethynylphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrO |
| Molecular Weight | 197.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
Related Bromo Standards
- 4-Bromo-1H-pyrrolo[3,2-c]pyridine (CAS 1000342-68-6)
- 6-Bromo-5-azaindole, 97% (CAS 1000342-71-1)
- 2-Bromo-5-cyano-6-picoline (CAS 1003711-39-4)
- 2-Bromo-1H-pyrrolo[2,3-b]pyridine (CAS 1083181-25-2)
- Methyl 2-bromo-4-hydroxybutanoate (CAS 111044-01-0)
- 2-Bromo-6-(cyanomethyl)pyridine (CAS 112575-11-8)
- 3-Bromo-3H-pyrrolo[2,3-b]pyridine (CAS 1160790-59-9)
- 5-Bromo-6-methylpicolinonitrile (CAS 1173897-86-3)
Recommended Standards
- 2-Bromo-5-methylnicotinonitrile (CAS 65996-18-1)
- 2-Bromo-6-methylisonicotinonitrile (CAS 25462-99-1)
- 2-Bromo-5-ethynylphenol (CAS 2353678-02-9)
- 2-Bromobenzofuran (CAS 54008-77-4)
- 4-(1H-Tetrazol-5-yl-methyl)-4H-benzo[1,4]thiazin-3-one (CAS 874765-99-8)
- Methyl 3-methoxy-2-(trifluoromethyl)benzoate (CAS 1214375-41-3)
- 3-(2-fluorophenoxy)-2-butanone (CAS 30343-27-2)
- 3-bromo-4-chlorofuro[2,3-b]pyridine (CAS 220939-67-3)
- 4-(4-(4-Aminobenzoyl)piperazin-1-yl)benzonitrile (CAS 885949-73-5)
- Dimethyl 3'-(trifluoromethyl)-[1,1'-biphenyl]-3,5-dicarboxylate (CAS 887582-99-2)
- (2R,4S)-Benzyl 4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1279200-14-4)
- 2,5-Furandione, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol and 2-(hydroxymethyl)-2-methyl-1,3-propanediol (CAS 74499-73-3)
- 2-(1-(4-Chlorobenzyl)-2,5-dimethyl-1h-indol-3-yl)-N-(2-methoxypyridin-4-yl)-2-oxoacetamide (CAS 1006604-91-6)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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