4-Bromo-2-ethynyl-6-fluorophenol CAS 2229369-27-9
| CAS No. | 2229369-27-9 |
| Molecular Formula | C8H4BrFO |
| Molecular Weight | 215.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-2-ethynyl-6-fluorophenol (CAS 2229369-27-9) is a high-purity analytical reference standard with the molecular formula C8H4BrFO and a molecular weight of 215.02 g/mol.
4-Bromo-2-ethynyl-6-fluorophenol (C8H4BrFO) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4BrFO |
| Molecular Weight | 215.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 5-Bromo-6-fluoro-1H-benzo[d]imidazole (CAS 1008360-84-6)
- 5-Bromo-4-fluoro-1H-benzo[d]imidazole, 97% (CAS 1008361-72-5)
- 5-Bromo-6-fluoro-1H-indazole (CAS 105391-70-6)
- 4-Bromo-5-fluoroindazole (CAS 1056264-22-2)
- 2-Bromo-6-fluoroimidazo[1,2-α]pyridine (CAS 1060815-08-8)
- 7-Bromo-4-fluoro-1H-pyrrolo[3,2-c]pyridine (CAS 1082041-10-8)
- 5-Bromo-4-fluoro-1H-indazole (CAS 1082041-85-7)
- 5-Bromo-3-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1111637-68-3)
Recommended Standards
- 4-Amino-3-bromo-5-fluorobenzonitrile (CAS 874880-58-7)
- 4-Bromo-5-fluorobenzofuran (CAS 286836-29-1)
- 4-Amino-3-bromo-2-fluorobenzonitrile (CAS 2090323-74-1)
- 4-Bromo-6-fluoro-1-benzofuran (CAS 325487-80-7)
- 2,2,2-Trifluoroethyl (5-methylpyridin-2-yl)carbamate (CAS 1087798-14-8)
- tert-Butyl 3-(bromomethyl)-5-chloro-1H-indole-1-carboxylate (CAS 168143-76-8)
- 3,5-Dichloro-6-(2-fluorophenyl)-1-methylpyrazin-2(1H)-one (CAS 1269533-60-9)
- Tert-butyl (4S,5R)-4-(hydroxymethyl)-2,2,5-trimethyloxazolidine-3-carboxylate (CAS 1264520-06-0)
- Amino((1-aza-3-methylbut-1-enyl)amino)methanethione (CAS 21009-72-3)
- 4-(1-Aminoethyl)-1-methyl-1H-indazole (CAS 1120214-87-0)
- Dicyclohexyl[3-methoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine (CAS 2118959-59-2)
- 3-(3-Fluorophenyl)-1H-indazol-7-amine (CAS 473410-09-2)
- N-([1,1'-Biphenyl]-2-yl)-2-((4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 577988-98-8)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com