1,4-Dihydroxy-2-(hydroxymethyl)anthracene-9,10-dione CAS 22296-59-9
| CAS No. | 22296-59-9 |
| Molecular Formula | C15H10O5 |
| Molecular Weight | 270.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,4-Dihydroxy-2-(hydroxymethyl)anthracene-9,10-dione (C15H10O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1,4-Dihydroxy-2-(hydroxymethyl)anthracene-9,10-dione (CAS 22296-59-9), molecular formula C15H10O5 and molecular weight 270.24 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10O5 |
| Molecular Weight | 270.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
Related Dihydroxy Standards
- 4,5-Dihydroxy-1-(hydroxymethyl)anthracene-9,10-dione (CAS 128341-04-8)
- 1,6-Dihydroxy-2-methoxyanthracene-9,10-dione (CAS 142878-32-8)
- 1,5-Dihydroxy-2-methoxyanthracene-9,10-dione (CAS 157029-68-0)
- 1,4-Dihydroxy-6-methoxyanthracene-9,10-dione (CAS 72473-66-6)
- 1,5-Dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione (CAS 59190-73-7)
- 5,7-Dihydroxy-2-(2-hydroxyphenyl)-4H-chromen-4-one (CAS 73046-40-9)
- 5,7-Dihydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one (CAS 72472-92-5)
- 7,8-Dihydroxy-2-(2-hydroxyphenyl)-4H-chromen-4-one (CAS 263407-44-9)
Recommended Standards
- 1,4,5-Trihydroxy-2-methylanthracene-9,10-dione (CAS 476-56-2)
- 1,2-Bis(4-nitrophenyl)ethene (CAS 2501-02-2)
- 1,5,8-Trihydroxy-3-methylanthracene-9,10-dione (CAS 518-80-9)
- 1,2,8-Trihydroxy-3-methylanthracene-9,10-dione (CAS 58322-78-4)
- 1-Propylquinazolin-4(1H)-one (CAS 3476-69-5)
- 1-(3-Phenylpropyl)piperazin-2-one (CAS 198896-29-6)
- N-(2-methylbenzyl)-1-phenylethan-1-amine hydrochloride (CAS 1048640-81-8)
- 4-methoxy-N-methyl-pyridin-2-amine (CAS 1104455-24-4)
- 5-Amino-1-(5-chloro-2-methylphenyl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 2197063-33-3)
- (2R)-2-((1H-Indol-3-yl)methyl)thiazolidine-4-carboxylic acid (CAS 111961-85-4)
- N-isobutyl-2-methylcyclohexan-1-amine (CAS 1019582-16-1)
- 1-[2-(4-Chlorophenoxy)ethyl]-4-{[6-(trifluoromethyl)-3-pyridinyl]methyl}-1,4-diazepan-5-one (CAS 909659-29-6)
- 1-(3-chloro-4,4,4-trifluoro-2-phenylbut-2-enyl)piperidine (CAS 256529-21-2)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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