3-(2-Bromo-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)piperidine-2,6-dione CAS 2229724-66-5
| CAS No. | 2229724-66-5 |
| Molecular Formula | C12H10BrN3O3 |
| Molecular Weight | 324.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2-Bromo-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)piperidine-2,6-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(2-Bromo-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)piperidine-2,6-dione (CAS 2229724-66-5), molecular formula C12H10BrN3O3 and molecular weight 324.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2-Bromo-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)piperidine-2,6-dione (C12H10BrN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(2-Bromo-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)piperidine-2,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10BrN3O3 |
| Molecular Weight | 324.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 2-Amino-6-(4-bromophenyl)pyridine-3,4,5-tricarbonitrile (CAS 478068-14-3)
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- 2-(n-Methyl5-bromofuran-2-amido)benzoic acid (CAS 953717-14-1)
- 6-Bromo-3-iodo-1-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 2231673-15-5)
- 2,4-dimethyl-5-phenylimidazo[1,5-b]pyridazine-7-thiol (CAS 54221-54-4)
- 2-({[2-({[2-Carboxycyclohexyl]carbonyl}anilino)ethyl]anilino}carbonyl)cyclohexanecarboxylic acid (CAS 1212289-11-6)
- N-(2-(cyclohex-1-en-1-yl)ethyl)-2-iodobenzamide (CAS 692266-60-7)
- 2-(Pyridin-4-yl)quinoline (CAS 52089-02-8)
- 2-Bromo-5-(trifluoromethoxy)pyrazine (CAS 1261808-28-9)
- Ethyl 2-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,10-dihydrophenanthren-2-yl)acetate (CAS 1423702-47-9)
- 2-Amino-4-cyano-1H-imidazole-5-carboxylic acid (CAS 125815-69-2)
- Methyl 5-bromo-3-methyl-2-nitrobenzoate (CAS 1805470-68-1)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
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