(R)-Elexacaftor CAS 2229860-99-3
| CAS No. | 2229860-99-3 |
| Molecular Formula | C26H34F3N7O4S |
| Molecular Weight | 597.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-Elexacaftor.
(R)-Elexacaftor (CAS 2229860-99-3), molecular formula C26H34F3N7O4S and molecular weight 597.65 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (R)-Elexacaftor (C26H34F3N7O4S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 597.65 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-Elexacaftor meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H34F3N7O4S |
| Molecular Weight | 597.65 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related R Standards
Recommended Standards
- Avacopan Impurity 1 (CAS CATO-C4X-29451)
- 8-Methoxycarbonyloctyl 2-deoxy-4-6-O-(4-methoxybenzylidene)-2-phthalimido-β-D-glucopyranoside (CAS 359436-88-7)
- Relugolix Impurity 39 (CAS 2814571-33-8)
- m-PEG10-NHS ester (CAS 2490419-63-9)
- 2-Hydrazinylbenzonitrile (CAS 63589-18-4)
- 1-cyano-3-(methylmercurio)guanidine (CAS 502-39-6)
- 3-Chloro-6-methoxypyridine-2-carboxylic Acid (CAS 856836-44-7)
- 2-((1-(3-Fluorophenyl)ethyl)amino)propan-1-ol (CAS 1154991-81-7)
- (2-Bromophenyl)(4-(5-(thiophen-3-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone (CAS 1448073-36-6)
- 1-(2,2-Difluoroethyl)-3-(isopropoxymethyl)-1H-pyrazole (CAS 1855951-75-5)
- 2,3-Dichloro-3-(1,3-dioxolan-2-yl)benzophenone (CAS 898759-49-4)
- 210644-48-7 Anthranilyl-HIV Protease Substrate V (CAS 210644-48-7)
- 2-(Methylthio)-5-phenylpyrimidin-4(1H)-one (CAS 61044-90-4)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com