(R)-1-(3-(Difluoromethyl)-2-methylphenyl)ethan-1-amine hydrochloride CAS 2230840-57-8
| CAS No. | 2230840-57-8 |
| Molecular Formula | C10H13F2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-1-(3-(Difluoromethyl)-2-methylphenyl)ethan-1-amine hydrochloride.
(R)-1-(3-(Difluoromethyl)-2-methylphenyl)ethan-1-amine hydrochloride (CAS 2230840-57-8) is a high-purity analytical reference standard with the molecular formula C10H13F2NHCl and a molecular weight of 221.67 g/mol.
Owing to a nitrile group, fluorine/chlorine substitution, (R)-1-(3-(Difluoromethyl)-2-methylphenyl)ethan-1-amine hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 221.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13F2N HCl |
| Molecular Weight | 221.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 2-(2-(Difluoromethyl)phenyl)acetic acid (CAS 1000517-62-3)
- 2-[4-(difluoromethyl)phenyl]acetic acid (CAS 1000524-74-2)
- 2-(4-(Difluoromethyl)phenyl)acetonitrile (CAS 1000529-64-5)
- 2-(3-(Difluoromethyl)phenyl)acetonitrile (CAS 1000529-78-1)
- 2-(4-(Difluoromethyl)phenyl)ethan-1-amine (CAS 1000539-08-1)
- 2-(3-(Difluoromethyl)phenyl)acetic acid (CAS 1000547-15-8)
- 2-(2-(Difluoromethyl)phenyl)acetonitrile (CAS 1000556-48-8)
- 2-(2-(Difluoromethyl)phenyl)ethanamine (CAS 1000559-85-2)
Recommended Standards
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- Ethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate (CAS 851460-85-0)
- 2-Chloro-6-(1-(3-fluorophenyl)ethoxy)pyrazine (CAS 426829-21-2)
- tert-Butyl 2-(naphthalen-1-ylmethyl)piperazine-1-carboxylate (CAS 886778-53-6)
- 2,4-Dimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 88268-24-0)
- 3-Bromo-5H,6H,7H-pyrrolo[3,4-b]pyridine dihydrochloride (CAS 1956382-38-9)
- 1-(Methylsulfonyl)piperazine hydrochloride (CAS 161357-89-7)
- 4-(9H-Purin-6-yl)-1-thia-4-azaspiro[5.5]undecane (CAS 1445143-90-7)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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