2-(1,1-Difluoroethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine CAS 2231122-95-3
| CAS No. | 2231122-95-3 |
| Molecular Formula | C13H18BF2NO2 |
| Molecular Weight | 269.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(1,1-Difluoroethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(1,1-Difluoroethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2231122-95-3) is a high-purity analytical reference standard with the molecular formula C13H18BF2NO2 and a molecular weight of 269.10 g/mol.
Structurally, 2-(1,1-Difluoroethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (C13H18BF2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.5, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 269.10 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18BF2NO2 |
| Molecular Weight | 269.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- Methyl 1-(2,2-difluoroethyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018141-97-3)
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Recommended Standards
- 2-(((4H-1,2,4-triazol-4-yl)amino)methyl)-4-bromophenol (CAS 728931-51-9)
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- (4-Chloro-3-fluorophenyl)(4-chlorophenyl)methanone (CAS 951890-56-5)
- 2,2,2-trifluoroethyl N-[(2,2,2-trifluoroethoxy)carbonyl]carbamate (CAS 2031269-45-9)
- Ethyl 5,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 185011-67-0)
- 2-Hydroxy-4-(pyrrolidin-1-yl)benzoic acid (CAS 539827-14-0)
- (5-(2-Methylthiazol-4-yl)thiophen-2-yl)methanamine (CAS 868238-07-7)
- Octafluoroadipoyl chloride (CAS 336-06-1)
- 3-methoxy-4-hydroxy-5-iodobenzaldehyde 4-Hydroxy-3-iodo-5-methoxybenzaldehyde 4-hydroxy-3-iodo-5-methoxy-benzaldehyde 4-hydroxy-5-iodo-3-methoxybenzaldehyde 5-Iodovanillin 5-iodo vanillin 5438-36-8 (CAS 5438-36-8)
- (2R,4R,5S,6R)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol (CAS 13299-16-6)
- 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic Acid 1,1-Dimethylethyl Ester (CAS 123387-51-9)
- (4-Bromophenyl)(piperidin-3-yl)methanone (CAS 1017367-02-0)
- 2-(4-Methoxyphenyl)pyridin-3-amine (CAS 663918-44-3)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
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