(1S,3s)-3-(fluoromethyl)cyclobutan-1-amine hydrochloride CAS 2231663-41-3
| CAS No. | 2231663-41-3 |
| Molecular Formula | C5H10FN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (1S,3s)-3-(fluoromethyl)cyclobutan-1-amine hydrochloride (C5H10FNHCl) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies (1S,3s)-3-(fluoromethyl)cyclobutan-1-amine hydrochloride (CAS 2231663-41-3), a certified reference material (molecular formula C5H10FNHCl, MW 139.60 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1S,3s)-3-(fluoromethyl)cyclobutan-1-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H10FN HCl |
| Molecular Weight | 139.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 5-(Trifluoromethoxy)-1H-benzo[d][1,2,3]triazole (CAS 157590-69-7)
- 4-ethylthiazol-2-amine (CAS 34631-53-3)
- (1R,2RS,4SR,5RS)-2-((SR)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidine 1-oxide (CAS CATO-C4X-27509)
- 2-Methylquinoline-6-boronic acid pinacol ester, 97% (CAS 1022090-86-3)
- (((4-(Phenyldiazenyl)benzyl)oxy)carbonyl)proline (CAS 194541-47-4)
- 5-Nitrobenzo[c][1,2,5]oxadiazol-4-ol (CAS 22250-52-8)
- O-(2-tert-Butoxy-ethyl)-hydroxylamine hydrochloride (CAS 1260836-58-5)
- 1,10-Decane-d20-diol (CAS 347841-78-5)
- 2-Fluoro-4-(tetrahydro-2H-pyran-4-yl)pyridine (CAS 1350356-56-7)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com