(R)-2-(3,3-difluorocyclohexyl)acetic acid CAS 2231664-80-3
| CAS No. | 2231664-80-3 |
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-2-(3,3-difluorocyclohexyl)acetic acid.
CATO supplies (R)-2-(3,3-difluorocyclohexyl)acetic acid (CAS 2231664-80-3), a certified reference material (molecular formula C8H12F2O2, MW 178.18 g/mol) for analytical method development and quality control.
The molecular framework of (R)-2-(3,3-difluorocyclohexyl)acetic acid (C8H12F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (R)-2-(3,3-difluorocyclohexyl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related R Standards
- 2-(3,3-Difluorocyclohexyl)acetic acid (CAS 1553621-50-3)
- (S)-2-(3,3-difluorocyclohexyl)acetic acid (CAS 2231666-42-3)
- 2-(4,4-Difluorocyclohexyl)acetic Acid (CAS 915030-40-9)
- 3-(4,4-Difluorocyclohexyl)propan-1-ol (CAS 1782085-58-8)
- 2-(4,4-Difluorocyclohexyl)propan-2-ol (CAS 2228363-86-6)
- 2-(4,4-Difluorocyclohexyl)-N-methylethan-1-amine (CAS 1555857-93-6)
- 3-(4,4-Difluorocyclohexyl)azetidine (CAS 2229318-08-3)
- 3-(4,4-Difluorocyclohexyl)-3-oxopropanenitrile (CAS 1546403-48-8)
Recommended Standards
- (E)-3-(4-hydroxy-2-methylphenyl)acrylic acid (CAS 927438-49-1)
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- (R)-chromane-2-carboxylic acid (CAS 83780-47-6)
- 1-(4-((6-Bromopyridin-2-yl)methyl)azepan-1-yl)ethan-1-one (CAS 1316221-34-7)
- Methyl 3-((2-hydroxyethyl)amino)benzoate (CAS 1225894-05-2)
- Methyl 3-(hydroxymethyl)-1H-indole-5-carboxylate (CAS 947412-98-8)
- Methyl 3-aminopentanoate hydrochloride (CAS 119924-95-7)
- Nicotinamide Impurity 7 (CAS 114-33-0)
- Bephenium (CAS 7181-73-9)
- (5-Cyclopropoxy-6-methoxypyridin-3-yl)methanamine (CAS 1243381-80-7)
- N4-(5-Chloro-2-hydroxyphenyl)-N2-isobutyl-L-asparagine (CAS 1098632-46-2)
- 2-Methoxy-1-methyl-1,2-dihydroquinoline (CAS 16021-66-2)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
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