(4-(Trifluoromethoxy)cyclohexyl)methanamine CAS 2231675-28-6
| CAS No. | 2231675-28-6 |
| Molecular Formula | C8H14F3NO |
| Molecular Weight | 197.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-(Trifluoromethoxy)cyclohexyl)methanamine (CAS 2231675-28-6) is a high-purity analytical reference standard with the molecular formula C8H14F3NO and a molecular weight of 197.20 g/mol.
The molecular framework of (4-(Trifluoromethoxy)cyclohexyl)methanamine (C8H14F3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14F3NO |
| Molecular Weight | 197.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- (3-(Trifluoromethoxy)cyclohexyl)methanamine (CAS 2231673-73-5)
- 2-methyl-4-(trifluoromethoxy)aniline (CAS 86256-59-9)
- 1-[4-(TRIFLUOROMETHOXY)PHENYL]METHANAMINE 4-(Trifluoromethoxy)benzylamine 93919-56-3 AS01945 LABOTEST-BB LT02090844 LABOTEST-BB LT03332148 LABOTEST-BB LT03496178 P-(TRIFLUOROMETHOXY)BENZYLAMINE RARECHEM AL BW 0449 [4-(TRIFLUOROMETHOXY)PHENYL]METHANAMINE (CAS 93919-56-3)
- 3-(Trifluoromethoxy)chlorobenzene (CAS 772-49-6)
- 4-(Trifluoromethoxy)chlorobenzene (CAS 461-81-4)
- 1-((Trifluoromethoxy)methyl)cyclobutane-1-carboxylic acid (CAS 1408279-33-3)
- 2-(cis-3-(Trifluoromethoxy)cyclobutyl)acetic acid (CAS 2489409-55-2)
- cis-[4-(trifluoromethoxy)cyclohexyl]methanol (CAS 1932060-96-2)
Recommended Standards
- (4-Amino-1-(trifluoromethyl)cyclohexyl)methanol (CAS 2770347-27-6)
- (2Z)-2-Amino-3-[(E)-[(pyridin-3-yl)methylidene]amino]but-2-enedinitrile (CAS 58259-74-8)
- [1-methyl-4-(trifluoromethyl)-4-piperidyl]methanol (CAS 2227206-66-6)
- (2Z)-2-Amino-3-[(E)-[(pyridin-2-yl)methylidene]amino]but-2-enedinitrile (CAS 58259-75-9)
- 4-Methyl-6-(propan-2-yl)-1,3,5-triazin-2-amine (CAS 82020-89-1)
- 2-Isopropyl-1,5-dimethyl-1H-benzo[d]imidazole (CAS 303747-39-9)
- 4-Isopropoxybenzofuran-6-amine (CAS 1330754-50-1)
- 4-(Dipropylamino)benzaldehyde (CAS 613-28-5)
- 1-Butyl-3-nitro-1H-pyrazole-4-carboxamide (CAS 61717-02-0)
- (3R,3aS)-3a,4-Dihydro-3-(hydroxymethyl)-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H,3H-oxazolo[4,3-c][1,4]benzoxazin-1-one (CAS 1427171-69-4)
- 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,5-dichlorobenzoic acid (CAS 1546542-85-1)
- Sitagliptin Impurity 102 (CAS CATO-C4X-1144102)
- 4-Fluorocyclohex-3-en-1-amine (CAS 675112-72-8)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com