(3-(Difluoromethyl)azetidin-3-yl)methanol CAS 2231676-14-3
| CAS No. | 2231676-14-3 |
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(3-(Difluoromethyl)azetidin-3-yl)methanol (CAS 2231676-14-3), molecular formula C5H9F2NO and molecular weight 137.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (3-(Difluoromethyl)azetidin-3-yl)methanol is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 137.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), (3-(Difluoromethyl)azetidin-3-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
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Recommended Standards
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- (4,4-Difluoropyrrolidin-3-yl)methanol (CAS 763060-99-7)
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- 3-Chloronaphthalene-2-sulfonyl chloride (CAS 3623-96-9)
- 3-(chloromethyl)-5H,6H,7H-[1,3]thiazolo[3,2-a]pyrimidine hydrochloride (CAS 62835-29-4)
- 2-(Isoquinolin-6-yl)propanoic acid (CAS 1195177-68-4)
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- 1,5-Dimethyl-1H-pyrazolo[3,4-b]pyrazin-3-amine (CAS 500731-38-4)
- 4-Chloro-1-methyl-1h-imidazole-5-carbaldehyde (CAS 193804-98-7)
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- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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