2-(1-(Tert-butoxycarbonyl)-3-fluoroazetidin-3-yl)-2-methylpropanoic acid CAS 2231677-12-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2231677-12-4
Molecular FormulaC12H20FNO4
Molecular Weight261.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(1-(Tert-butoxycarbonyl)-3-fluoroazetidin-3-yl)-2-methylpropanoic acid CAS 2231677-12-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1-(Tert-butoxycarbonyl)-3-fluoroazetidin-3-yl)-2-methylpropanoic acid.

2-(1-(Tert-butoxycarbonyl)-3-fluoroazetidin-3-yl)-2-methylpropanoic acid (CAS 2231677-12-4) is a high-purity analytical reference standard with the molecular formula C12H20FNO4 and a molecular weight of 261.29 g/mol.

The molecular framework of 2-(1-(Tert-butoxycarbonyl)-3-fluoroazetidin-3-yl)-2-methylpropanoic acid (C12H20FNO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H20FNO4
Molecular Weight261.29 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF-containing
Nitrogen Atoms1

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