2-Phenylpyrrolidine-1-carbonyl chloride CAS 223375-92-6

Purity 97%+In StockPharmaceutical Standards
CAS No.223375-92-6
Molecular FormulaC11H12ClNO
Molecular Weight209.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Phenylpyrrolidine-1-carbonyl chloride CAS 223375-92-6 chemical structure

Description

The occurrence of 2-Phenylpyrrolidine-1-carbonyl chloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Phenylpyrrolidine-1-carbonyl chloride (CAS 223375-92-6) is a high-purity analytical reference standard with the molecular formula C11H12ClNO and a molecular weight of 209.67 g/mol.

2-Phenylpyrrolidine-1-carbonyl chloride (C11H12ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Phenylpyrrolidine-1-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H12ClNO
Molecular Weight209.67 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2020
Halogen ContentCl-containing
Nitrogen Atoms1

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