6-Bromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one CAS 223420-41-5

Purity 97%+In StockPharmaceutical Standards
CAS No.223420-41-5
Molecular FormulaC10H7BrO4
Molecular Weight271.06 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one CAS 223420-41-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 271.06 g/mol gives 6-Bromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

6-Bromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one (CAS 223420-41-5), molecular formula C10H7BrO4 and molecular weight 271.06 g/mol, is a CATO reference standard with documented purity and traceability.

6-Bromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one (C10H7BrO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Bromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7BrO4
Molecular Weight271.06 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2020
Halogen ContentBr-containing

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