(3,4-Dichlorophenyl)(4-fluoro-4-(hydroxymethyl)piperidin-1-yl)methanone CAS 223632-79-9
| CAS No. | 223632-79-9 |
| Molecular Formula | C13H14Cl2FNO2 |
| Molecular Weight | 306.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3,4-Dichlorophenyl)(4-fluoro-4-(hydroxymethyl)piperidin-1-yl)methanone.
(3,4-Dichlorophenyl)(4-fluoro-4-(hydroxymethyl)piperidin-1-yl)methanone (CAS 223632-79-9) is a high-purity analytical reference standard with the molecular formula C13H14Cl2FNO2 and a molecular weight of 306.16 g/mol.
The molecular framework of (3,4-Dichlorophenyl)(4-fluoro-4-(hydroxymethyl)piperidin-1-yl)methanone (C13H14Cl2FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (3,4-Dichlorophenyl)(4-fluoro-4-(hydroxymethyl)piperidin-1-yl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14Cl2FNO2 |
| Molecular Weight | 306.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- tert-Butyl (3-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-yl)carbamate (CAS 1935484-73-3)
- 7-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1094260-88-4)
- (2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)methanamine (CAS 500731-75-9)
- Ethyl 5-(1,3-dioxolan-2-yl)-2-thiophenecarboxylate (CAS 898772-08-2)
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- 2-Amino-N-(3-methoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide (CAS 727656-12-4)
- N-(4-Fluorobenzo[d]thiazol-2-yl)-2-(4-(methylthio)phenyl)acetamide (CAS 942007-87-6)
- 5-Chloro-2-sulfanylbenzonitrile (CAS 38244-31-4)
- [Nva12]-Tirzepatide (CAS CATO-C4X-324042)
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