2-Bromo-1-(2-fluoro-6-(trifluoromethyl)phenyl)ethanone CAS 223785-85-1
| CAS No. | 223785-85-1 |
| Molecular Formula | C9H5BrF4O |
| Molecular Weight | 285.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Bromo-1-(2-fluoro-6-(trifluoromethyl)phenyl)ethanone (CAS 223785-85-1) is a high-purity analytical reference standard with the molecular formula C9H5BrF4O and a molecular weight of 285.03 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-Bromo-1-(2-fluoro-6-(trifluoromethyl)phenyl)ethanone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 285.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5BrF4O |
| Molecular Weight | 285.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 3-(4-Bromo-2-fluorophenyl)-1,1,1-trifluoropropan-2-one (CAS 1341616-28-1)
- 3-(5-Bromo-2-fluorophenyl)-1,1,1-trifluoropropan-2-one (CAS 1342005-54-2)
- 3-(2-Bromo-4-fluorophenyl)-1,1,1-trifluoropropan-2-one (CAS 1343587-98-3)
- 3-(3-Bromo-5-fluorophenyl)-1,1,1-trifluoropropan-2-one (CAS 1525763-88-5)
- 1-(6-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)ethanone (CAS 1823321-62-5)
- 1-Bromo-4-((1,3,3,3-tetrafluoroprop-1-en-1-yl)oxy)benzene (CAS 1824865-81-7)
- (Z)-1-bromo-4-((2,3,3,3-tetrafluoroprop-1-en-1-yl)oxy)benzene (CAS 1824879-04-0)
- 1-(2-Bromo-6-fluoro-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 2091610-87-4)
Recommended Standards
- 1-(4-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 2384288-98-4)
- 2-Bromo-1-(3-fluoro-4-(trifluoromethyl)phenyl)ethan-1-one (CAS 544429-22-3)
- 2-Bromo-1-(3-fluoro-5-(trifluoromethyl)phenyl)ethanone (CAS 202664-38-8)
- 1-(2,6-Difluoro-4-iodopyridin-3-yl)ethan-1-ol (CAS 2863532-61-8)
- 4-Bromo-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid (CAS 1643570-61-9)
- Tert-butyl (S)-4-(4-bromobenzyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide (CAS 1105712-06-8)
- 1-(4-Iodophenyl)tetrazole (CAS 249291-82-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(p-tolyl)thiazol-5-yl)boronate (CAS 2223050-48-2)
- Boc-4-iodo-L-phenylalanine Methyl Ester (CAS 113850-76-3)
- 2-amino-3H,4H-benzo[g]quinazolin-4-one (CAS 33987-05-2)
- 5-CFDA-AM, 90%, single isomer (CAS 124412-00-6)
- 3-(Chlorosulfonyl)-2,6-difluorobenzoic Acid (CAS 142576-91-8)
- Pyroxasulfone-sulfonic acid sodium (CAS 2832005-66-8)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
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