4-(4-Aminophenyl)-2-piperazinone CAS 223786-04-7
| CAS No. | 223786-04-7 |
| Molecular Formula | C10H13N3O |
| Molecular Weight | 191.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-Aminophenyl)-2-piperazinone (C10H13N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-(4-Aminophenyl)-2-piperazinone (CAS 223786-04-7) is a high-purity analytical reference standard with the molecular formula C10H13N3O and a molecular weight of 191.23 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(4-Aminophenyl)-2-piperazinone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H13N3O |
| Molecular Weight | 191.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Nitrogen Atoms | 3 |
Related Aminophenyl Standards
- 1-(4-Aminophenyl)-3-cyclopropylurea (CAS 1000931-26-9)
- 1-(3-Aminophenyl)piperazin-2-one (CAS 1022128-80-8)
- 1-(4-Aminophenyl)piperazin-2-one (CAS 1022128-82-0)
- 1-(3-Aminophenyl)-3-cyclopropylurea (CAS 1041603-13-7)
- 1-[(2-aminophenyl)methyl]imidazolidin-2-one (CAS 1062404-58-3)
- (4-Aminophenyl)(pyrazolidin-1-yl)methanone (CAS 1135283-70-3)
- 1-(4-Aminophenyl)-3-(prop-2-en-1-yl)urea (CAS 1223584-12-0)
- 1-(3-aminophenyl)-5-methylimidazolidin-2-one (CAS 1240528-94-2)
Recommended Standards
- 4-(3-Oxobutyl)benzamide (CAS 74248-67-2)
- 4-(6-Vinylpyridazin-3-yl)morpholine (CAS 223556-25-0)
- 4-(3-Methoxypropoxy)benzonitrile (CAS 943150-79-6)
- 4-(Cyclobutylamino)benzoic acid (CAS 518335-94-9)
- Pcb No. 3 (CAS 2051-62-9)
- 4-(7-Methoxybenzofuran-2-carboxamido)butanoic acid (CAS 503616-39-5)
- Bicyclo[2.2.1]Heptan-2-ylmethyl acetate (CAS 53075-46-0)
- Ethyl 3-(5-Nitropyridin-2-Yl)Benzoate (CAS 1258391-89-7)
- tert-Butyl 4-(((2-chloro-6-methylpyrimidin-4-yl)amino)methyl)piperidine-1-carboxylate (CAS 1261231-29-1)
- 3-(Bromomethyl)-1-ethyl-1H-pyrazole hydrobromide (CAS 1855907-56-0)
- 1-(2,5-Dichlorophenyl)-N,5-dimethyl-1H-1,2,4-triazole-3-carboxamide (CAS 338398-54-2)
- 4-Chlorophenylalaninol Hydrochloride (CAS 1379971-06-8)
- [S(R)]-N-[(S)-[2-(Di-tert-butylphosphino)phenyl[(2-naphthalenyl)methyl]-2-methyl-2-propanesulfinamide (CAS 2565792-62-1)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com