4,4'-Dibromo-2,2',6,6'-tetramethyl-1,1'-biphenyl CAS 22409-76-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,4'-Dibromo-2,2',6,6'-tetramethyl-1,1'-biphenyl.

CATO supplies 4,4'-Dibromo-2,2',6,6'-tetramethyl-1,1'-biphenyl (CAS 22409-76-3), a certified reference material (molecular formula C16H16Br2, MW 368.11 g/mol) for analytical method development and quality control.

4,4'-Dibromo-2,2',6,6'-tetramethyl-1,1'-biphenyl (C16H16Br2) contains bromine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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