Dabigatran Impurity 50 CAS 2243727-83-3
| CAS No. | 2243727-83-3 |
| Molecular Formula | C38H49N7O5 |
| Molecular Weight | 683.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Dabigatran Impurity 50 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 683.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Dabigatran Impurity 50 (CAS 2243727-83-3) is a certified pharmaceutical impurity reference standard with the molecular formula C38H49N7O5 and a molecular weight of 683.84 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C38H49N7O5 |
| Molecular Weight | 683.84 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 7 |
Related Dabigatran Standards
- Dabigatran Impurity 99 (CAS CATO-C4X-108999)
- Dabigatran Impurity 98 (CAS CATO-C4X-108998)
- Dabigatran Impurity 142 (CAS CATO-C4X-1089142)
- Dabigatran Impurity 148 (CAS CATO-C4X-1089148)
- Dabigatran Impurity 150 (CAS CATO-C4X-1089150)
- Dabigatran Impurity 32 (CAS CATO-C4X-108932)
- Dabigatran Impurity 72 (CAS 637238-96-0)
- Dabigatran Impurity 146 (CAS CATO-C4X-1089146)
Recommended Standards
- Benzyl N-[(2’-(Trityltetrazol-5-yl-1,1’-biphenyl-4-yl]-methyl-2-amino-3-methylbutanoate (CAS 1798894-89-9)
- (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-ol (CAS 81794-13-0)
- Benzyl N-[(2'-(trityltetrazol-5-yl-1,1'-biphenyl-4-yl]-methyl-2-amino-3-methylbutanoate (CAS 137864-45-0)
- (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-ol (CAS 81794-12-9)
- Allisartan Isoproxil Impurity 36 (CAS CATO-C4X-321736)
- Midecamycin Impurity 9 (CAS CATO-C4X-31229)
- Arotinolol Impurity 34 (CAS CATO-C4X-185434)
- n-Ethoxy-3-oxo-3,4-dihydro-2h-benzo[b][1,4]thiazine-6-carboxamide (CAS 923199-25-1)
- Ethoxysulfuron (CAS 126801-58-9)
- Tert-butyl 2-cyano-2-(3-nitropyridin-2-yl)acetate (CAS 123846-70-8)
- Finerenone Impurity 162 (CAS CATO-C4X-2880162)
- 1-(Tert-butyl) 2-methyl (2R,3S)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)pyrrolidine-1,2-dicarboxylate (CAS 2437327-98-3)
- 1,2-Epoxy-5-hexene (CAS 10353-53-4)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com