1,3-Difluoro-2-(2-fluoro-4-methylphenoxy)-5-(trifluoromethyl)benzene CAS 2244084-06-6

Purity 97%+In StockPharmaceutical Standards
CAS No.2244084-06-6
Molecular FormulaC14H8F6O
Molecular Weight306.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,3-Difluoro-2-(2-fluoro-4-methylphenoxy)-5-(trifluoromethyl)benzene CAS 2244084-06-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 306.20 g/mol gives 1,3-Difluoro-2-(2-fluoro-4-methylphenoxy)-5-(trifluoromethyl)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1,3-Difluoro-2-(2-fluoro-4-methylphenoxy)-5-(trifluoromethyl)benzene (CAS 2244084-06-6), molecular formula C14H8F6O and molecular weight 306.20 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1,3-Difluoro-2-(2-fluoro-4-methylphenoxy)-5-(trifluoromethyl)benzene (C14H8F6O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H8F6O
Molecular Weight306.20 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentF-containing

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